Director, Protein Sciences, Biology
Company: Gilead Sciences, Inc.
Location: San Mateo
Posted on: May 12, 2022
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Job Description:
The Protein Therapeutics Department is seeking an experienced
and exceptional director to lead our Protein Chemistry Group. The
successful candidate will work in a collaborative environment to
mainly support the recombinant protein needs from our small
molecule drug discovery programs. He/she will be responsible for
leading the team efforts in recombinant protein sample preparation
to meet project needs in assays and screenings, biophysics
characterization, structural and MOA studies. Gilead Sciences Inc.
is a highly matrixed organization and the ability to work
effectively across multiple function groups is a key attribute for
this role. Experience in successful leading the development and
execution of recombinant protein expression and purification
strategy for programs in Immuno-Oncology and Virology field and a
strong understanding of enzymology and protein structure-function
relationship are highly desired. Responsibilities and Technical
Skills:- Lead cross-functional Protein Chemistry Group to develop
and execute recombinant protein expression, purification and
characterization strategies to ensure delivery of samples of high
quality that meet project needs- Oversee the outsourcing activity
of screening CROs, protocol transfer, production outsourcing and
quality validation of protein samples for drug discovery programs-
Lead and direct group effort to identify, assess and implement new
technologies to enhance our technical capability and working
efficiency- Excellent collaboration, communication, and
interpersonal skills are required to work with
Enzymology/Biophysics, High Throughput Discovery, crystallography
structure team, Mass Spectrometry and Bioinformatics functions to
create synergy in assisting drug discovery projects on their effort
of assay setup and high throughput screening, lead identification
and optimization and MOA studies- Strong experimental background in
supporting small molecule drug discovery programs, demonstrated
experience in recombinant protein expression in E. coli and insect
cell expression system, and deep understanding of enzymology,
protein biochemistry/biophysics and protein structural studies -
Must be able to work independently and effectively on multiple
programs in a fast-paced matrixed environment- Must be team and
detail-oriented, motivated, and results focused.Experience:PhD
and/or post-doctoral training in the area of biochemistry,
molecular biology or other related bioscience field with a minimum
of 8-10 years of directly relevant biotechnology or pharmaceutical
industry experience. Candidate must be detail-oriented with
excellent organizational and communication skills who enjoys
working in a fast-paced dynamic multi-disciplinary environment.
Preference will be given to candidates with proven track record of
success and a strong scientific background in protein enzymology,
biochemistry, structural studies as well as group management.For
jobs in the United States:As an equal opportunity employer, Gilead
Sciences Inc. is committed to a diverse workforce. Employment
decisions regarding recruitment and selection will be made without
discrimination based on race, color, religion, national origin,
gender, age, sexual orientation, physical or mental disability,
genetic information or characteristic, gender identity and
expression, veteran status, or other non-job related
characteristics or other prohibited grounds specified in applicable
federal, state and local laws. In order to ensure reasonable
accommodation for individuals protected by Section 503 of the
Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment
Act of 1974, and Title I of the Americans with Disabilities Act of
1990, applicants who require accommodation in the job application
process may contact for assistance.Following extensive monitoring,
research, consideration of business implications and advice from
internal and external experts, Gilead has made the decision to
require all U.S. employees and contractors to receive the COVID-19
vaccines as a condition of employment. "Full vaccination" is
defined as two weeks after both doses of a two-dose vaccine or two
weeks since a single-dose vaccine has been administered. Anyone
unable to be vaccinated, either because of a sincerely held
religious belief or a medical condition or disability that prevents
them from being vaccinated, can request a reasonable
accommodation.---For more information about equal employment
opportunity protections, please view the 'EEO is the Law' poster.
NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE
FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION
PROVISION Our environment respects individual differences and
recognizes each employee as an integral member of our company. Our
workforce reflects these values and celebrates the individuals who
make up our growing team.Gilead provides a work environment free of
harassment and prohibited conduct. We promote and support
individual differences and diversity of thoughts and opinion.For
Current Gilead Employees and Contractors:Please log onto your
Internal Career Site to apply for this job.
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Keywords: Gilead Sciences, Inc., San Mateo , Director, Protein Sciences, Biology, Executive , San Mateo, California
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