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Scientist, Bioengineer

Company: Notable Labs
Location: san mateo
Posted on: May 3, 2021

Job Description:


* We are seeking an extremely versatile multidisciplinary scientist with an engineering mindset who is excited to utilize their cross functional expertise to develop scalable impactful platforms and technologies for interrogating biological systems to enable precision medicine

* The R&D group is responsible for creating new assays and troubleshooting experiments and technology on our platform. This requires a blend of scientific analysis and critical assessment of data with understanding of code and technology. The team interfaces with both vendors and scientific partners, often expanding the limits of new technologies in these partnerships. * Scientists within the Research & Development Group contribute to the development, scaling, and implementation of high throughput assays and workflows. This individual collaborates with teams of scientists and engineers upon projects to conceptualize, design, develop, and implement solutions to optimize the performance and efficiency of our existing assays. This individual also leads efforts developing and incorporating novel high throughput assays into Notables Platform for our hypothesis driven research projects focused on predicting patient response to different therapies across different blood cancers.


* Lead troubleshooting efforts, analyze complex data and drive key assay and process related decisions * Design and execute experiments that develop and characterize cell-based assays. Efforts may include: * Bringing new instruments and experimental techniques into the lab and developing assays into the R&D team * Finding optimal conditions for primary human cell culture * Characterizing variance and stability of assays at scale * Identifying and developing controls for sources of variability * Identifying and testing areas for process improvements * Lead cross-functional efforts with scientists, software engineers, hardware engineers, and team leaders throughout the company. You will be expected to discuss everything from early drug development to the physics behind flow cytometry with these groups. * Present designs and conclusions to a broad interdisciplinary audience


* Experience with the development of novel biological assays, technologies and methods (particularly for cell based assays) * Foundational understanding and experience with mammalian or primary cell culture, molecular & cell biology * PhD or MS in Biological Sciences, Bioengineering or related field with 0+ years (with PhD), 4+ years (with MS) of relevant experience required.

Nice to Haves

* Experience with primary cell culture or cancer co-culture models * Experience with Multicolor flow cytometry (10 color+) * Experience developing high throughput screening assays

* Familiarity with scripting in Python/R * Experience with NGS workflows * Expertise in hematopoiesis, hematological malignancies, or immuno-oncology

About You

* You have worked extensively in scientific research troubleshooting experiments and technologies. * You have experience with a wide variety of experimental techniques, and are excited to quickly develop expertise in very diverse fields. * You are the person others seek out to interpret the most confusing experimental data. * You have outstanding instincts in experimental design. You are adept at tailoring your controls to the goal of the experiment or process. * You are excited to lead the development of a culture that blends science and technology. You speak both science and engineering and are excited to act as a bridge between groups. * You strive to stretch out of your comfort zone and are motivated to tackle challenging problems.

Keywords: Notable Labs, San Mateo , Scientist, Bioengineer, Other , san mateo, California

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