Life Science Research Professional 2 (2 Years Fixed Term)
Company: Stanford Medicine
Location: San Mateo
Posted on: January 11, 2022
The Stanford Brain Organogenesis Program within the Department
of Psychiatry and Behavioral Sciences at Stanford University School
of Medicine is seeking a highly motivated Life Science Research
Professional 2 to join Dr. Sergiu Pasca ' s research program in a
2-year fixed term role.
Our Stanford research team seeks to understand the rules that
govern the molecular and cellular steps underlying the assembly of
the human brain and the molecular mechanisms that lead to
neurodevelopmental and neurodegenerative disorders. We are
developing bottom-up approaches to generate and assemble, from
multi-cellular components, human neural circuits. More
specifically, we have pioneered the generation from human
pluripotent stem cells of brain region-specific organoids ( Nature
Methods 2015; Neuron 2017; Nature Methods 2019; Nature Neuroscience
2019) and assembloids ( Nature 2017; Nature Biotechnology 2020;
Cell 2020), which we applied to gain mechanistic insights into
disease ( Nature Medicine 2018; Nature Medicine 2020). Our ultimate
goal is to identify novel and reliable drug targets for
The candidate for this position will join an enthusiastic and
multi-disciplinary team at Stanford, and should ideally have
experience with human stem cells, neural differentiation, primary
tissue culture or assay development and high-throughput
For more information on the Pasca lab and research being performed
please visit their website at www.pascalab.org .
- Independently conduct a portion of the research project(s)
related to building brain organoid and assembloid models. Make
recommendations on experimental design and/or research direction to
- Independently conduct experiments (cell culture, assay,
screens) to gather data for a portion of a major research
- Interpret and analyze results, often where few guidelines
exist, and make modifications to existing procedures and
- Participate in multidisciplinary teams across different
faculties or schools.
- Perform ongoing literature review to remain current with new
procedures and related research; apply to ongoing research and
development of new protocols.
- Contribute substantively to the preparation of papers for
publication, especially in the results section, and to publication
of findings. Present ongoing work to colleagues and/or academic
- Oversee supply and equipment budget under supervision of
principal investigator or business manager.
- Work with health and safety department to ensure lab complies
with regulations and all required trainings.
- Supervise (either formally or informally) staff or students as
needed, including oversight and direction on techniques, as well as
consultation on project work. Serve as a technical resource for
other research staff.
- Oversee the daily activities of the laboratory including lab
maintenance; maintain lab stock, manage chemical inventory and
safety records, and provide general lab support as needed. May
assist with purchasing laboratory equipment.
- - Other duties may also be assigned
- Knowledge and experience with neurobiology, stem cell biology,
molecular biology techniques and cellular assays
EDUCATION & EXPERIENCE (REQUIRED):
- Bachelor's degree in related scientific field and two years of
relevant work experience; or Master's degree in a related
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- Comprehensive understanding of scientific principles.
- General computer skills and ability to quickly learn and master
computer programs, databases, and scientific applications.
- Strong analytical skills and excellent judgment.
- Ability to maintain detailed records of experiments and
- Ability to work under deadlines with general guidance is
- Excellent organizational skills and demonstrated ability to
accurately complete detailed work.
- Frequently stand, walk, twist, bend, stoop, squat, grasp
lightly, use fine manipulation, grasp forcefully, perform
desk-based computer tasks, use telephone, write by hand, lift,
carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders,
sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand
and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder
level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous
- Position may require repetitive motion.
- - Consistent with its obligations under the law, the University
will provide reasonable accommodation to any employee with a
disability who requires accommodation to perform the essential
functions of his or her job.
- May require working in close proximity to blood borne
- May require work in an environment where animals are used for
teaching and research.
- Position may at times require the employee to work with or be
in areas where hazardous materials and/or infectious diseases are
- Employee must perform tasks that require the use of personal
protective equipment, such as safety glasses and shoes, protective
clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research
requirements and business needs.
- Interpersonal Skills: Demonstrates the ability to work well
with Stanford colleagues and clients and with external
- Promote Culture of Safety: Demonstrates commitment to personal
responsibility and value for safety; communicates safety concerns;
uses and promotes safe behaviors bases on training and lessons
- Subject to and expected to comply with all applicable
University policies and procedures, including but not limited to
the personnel policies and other policies found in the University's
Administrative Guide, http://adminguide.stanford.edu .
- Schedule: Full-time
- Job Code: 4952
- Employee Status: Fixed-Term
- Pay Grade: G
- Requisition ID: 90470As an organization that receives federal
funding, Stanford University has a COVID-19 vaccination requirement
that will apply to all university employees, including those
working remotely in the United States and applicable
subcontractors. To learn more about COVID policies and guidelines
for Stanford University Staff, please visit
Keywords: Stanford Medicine, San Mateo , Life Science Research Professional 2 (2 Years Fixed Term), Other , San Mateo, California
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