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Research Scientist, Biorepository

Company: Gilead Sciences, Inc.
Location: San Mateo
Posted on: November 19, 2022

Job Description:

Research Scientist, BiorepositoryUnited States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.Making an impact on a global scaleInclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly For Current Gilead Employees and Contractors:Please log onto your Internal Career Site to apply for this job.Job DescriptionGilead Sciences Protein Therapeutics department has an opportunity for highly motivated Research Scientist within the Protein Science group. In this position, the candidate will lead and develop the research logistics/biorepository team, which plays a pivotal role in the establishment and expansion of the cryo-bank at the state-of-the-art Foster City research facility, ensuring that logistical services to Gilead Sciences internal and external customers are provided in a timely manner. This process will include automated liquid handling and labeling of biotherapeutics that are tracked through Laboratory Information Management Software (LIMS). This process will evolve to include continuous planning of wet lab aliquoting of new inventory, archival updates, receipt of CRO generated lots, and provide logistical support for worldwide shipping. Responsibilities:

  • Manage the cryo-repository for Protein Therapeutics department (samples include proteins, bio-conjugates, DNA, etc)
  • Develop, optimize, and utilize protocols for biotherapeutic sample aliquoting, dilution/concentration normalization, and labeling
  • Lead the efforts in working with Research Informatics on configuration and optimization of reagent inventory software for sample request/approval/tracking
  • Work with cross-functional teams to ensure timely delivery of research samples to requesters
  • Generate, review and deliver CofA to internal and external customers
  • Perform re-QC for samples upon request
  • Coordinate with external facility for critical reagent repository
  • Plan strategic growth of research logistics team to support expanded needs of Protein Therapeutics department
  • Provide training and mentorship to junior staffEducation and Experience:
    • M.S. in Biology or Chemistry with a minimum of 6+ years of direct experience with listed characteristics and techniques for the position; and/or an equivalent combination of education and experience.Required skills
      • Strong analytical, communication, and organizational skills
      • Detailed scientific knowledge in molecular biology and protein biochemistry
      • Highly experienced in management and distribution reagent inventory software
      • Extensive hands-on experience in sample aliquoting using automated liquid handling systems (Hamilton, Biomek, Bravo, etc) in a sterile process
        • Proficiency with various analytical protein characterization/QC techniques such as concentration measurement, SDS-PAGE or CE-SDS, Endosafe, analytical SEC, freeze thaw test
        • Experience in DNA quality control such as sequencing and restriction digestionNice to have skills
          • Knowledge in protein formulation, protein characterization by Mass Spectroscopy (LC/MS-TOF), stability assessment is a plus
          • Experience in molecular cloning techniques (such as plasmid prep) is a strong plus
          • Experience in cell bank management is highly valued For jobs in the United States:As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S., Canada, Australia, Singapore, and Hong Kong employees and contractors to receive the COVID-19 vaccines as a condition of employment. "Full vaccination" is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.For Current Gilead Employees and Contractors:Please log onto your Internal Career Site to apply for this job.


Keywords: Gilead Sciences, Inc., San Mateo , Research Scientist, Biorepository, Other , San Mateo, California

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