Senior Research Scientist II, Formulation & Process Development

Company: Gilead Sciences, Inc.
Location: San Mateo
Posted on: January 15, 2023

Job Description:

Senior Research Scientist II, Formulation & Process DevelopmentUnited States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.Making an impact on a global scaleInclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly For Current Gilead Employees and Contractors:Please log onto your Internal Career Site to apply for this job.At Gilead we believe every employee deserves a great leader. As a people leader now or in the future, we expect that you will model and create an environment of inclusion, be intentionally focused on the hiring, development, growth and retention of talent, and empower teams to align and achieve goals.Job DescriptionSr. Research Scientist II - Formulation & Process DevelopmentGilead Sciences, Inc. is a research-based biopharmaceutical company founded in 1987. Together we deliver life-saving therapies to patients in need. With the commitment and drive you bring to the workplace every day, you will be part of a team that is changing the world and helping millions of people live healthier, more fulfilling lives. Our worldwide staff is a close community where you can see the tangible results of your contributions, where every individual matters, and everyone has a chance to enhance their skills through ongoing development. Our scientific focus has resulted in marketed products that are benefiting hundreds of thousands of people, a pipeline of late-stage drug candidates, and unmatched patient access programs to ensure medications are available to those who could otherwise not afford them. By joining Gilead, you will further our mission to address unmet medical needs and improve life by advancing the care of patients with life-threatening diseases.Gilead Sciences has an opportunity for an experienced candidate in our Formulation & Process Development group at our Headquarters in Foster City, CA. We are seeking motivated, team-oriented individuals with scientific experience with lab work related to small molecules.The Formulation & Process Development group located at the Foster City, CA Gilead headquarters is seeking a Senior Research Scientist I to provide scientific, technical and hands-on support of drug discovery and product development.The qualified candidate should have experience and/or knowledge in pre-formulation, formulation and process development, Quality by Design (QbD), oversight of GMP drug product manufacturing and global regulatory CMC (INDs, IMPDs, NDAs, MAAs). Experience in parenteral product development and sustained parenteral drug delivery is strongly preferred.The qualified candidate will be responsible for lead optimization, API form selection/characterization, pre-formulation, formulation development, manufacture of clinical supplies, development of efficient and scalable manufacturing processes, process scale up based on Quality by Design (QbD), implementation of innovative technologies, CMO management and global regulatory strategy.Essential Duties and Job Functions:

• Works with research teams to support drug discovery
• Responsible for development of small molecule formulations at all stages of clinical development
• Investigates the feasibility of applying advanced principles and techniques of related scientific specialty to products and problems.
• Works on complex problems where analysis of situations or data requires evaluation of intangible variables, requiring regular use of ingenuity and creativity.
• Exercises independent judgment in developing methods, techniques and evaluation criteria for obtaining results.
• May require managerial responsibilities
• Experienced in formulation and process development, manufacture, and scale-up of oral and/or small molecule parenteral drug products.
• Knowledge of basic analytical skills required: HPLC/UPLC, UV, solid state characterization.
• Excellent communication skills (both verbal and written) and interpersonal skills are required.
• Maintains full working knowledge of state-of-the art principles and theories, applying such knowledge to the direction that supports Company interests.
• Demonstrates technical proficiency, scientific creativity, collaboration with others and independent thought in suggesting experimental design and strategy.
• Must think critically and creatively and be able to work independently, determine appropriate resources for resolution of problems and have strong organizational and planning skills.Knowledge, Experience and Skills:
  • 7+ years of experience with PhD in a related scientific discipline
  • BS or MS degree with extensive industry experienceFor jobs in the United States:As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S., Canada, Australia, Singapore, and Hong Kong employees and contractors to receive the COVID-19 vaccines as a condition of employment. "Full vaccination" is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.For Current Gilead Employees and Contractors:Please log onto your Internal Career Site to apply for this job.
    
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Keywords: Gilead Sciences, Inc., San Mateo , Senior Research Scientist II, Formulation & Process Development, Other , San Mateo, California