Research Scientist, Drug Metabolism and Pharmacokinetics
Company: Gilead Sciences, Inc.
Location: San Mateo
Posted on: January 25, 2023
Job Description:
Research Scientist, Drug Metabolism and PharmacokineticsUnited
States - California - Foster CityGilead Sciences, Inc. is a
research-based bio-pharmaceutical company that discovers, develops
and commercializes innovative medicines in areas of unmet medical
need. With each new discovery and investigational drug candidate,
we seek to improve the care of patients living with
life-threatening diseases around the world. Gilead's therapeutic
areas of focus include HIV/AIDS, liver diseases, cancer and
inflammation, and serious respiratory and cardiovascular
conditions.Making an impact on a global scaleInclusion is one of
the company's five core values. That's because we know that we are
stronger and more innovative at Gilead when we are informed by a
diverse set of backgrounds, experiences and points of view. Gilead
Sciences is a biopharmaceutical company that discovers, develops
and commercializes innovative therapeutics in areas of unmet
medical need. The company's mission is to advance the care of
patients suffering from life-threatening diseases worldwide. When
you join Gilead, you join our mission to change the world by
enabling people to live healthier and more fulfilling lives. Come
join a mission-driven bio-pharmaceutical organization that values
inclusion and diversity, has a strong portfolio of products, and is
constantly For Current Gilead Employees and Contractors:Please log
onto your Internal Career Site to apply for this job.Job
DescriptionGilead Sciences, Inc. is a research-based
biopharmaceutical company that discovers, develops and
commercializes innovative medicines in areas of unmet medical need.
With each new discovery and investigational drug candidate, we seek
to improve the care of patients living with life-threatening
diseases around the world. Gilead's therapeutic areas of focus
include HIV/ AIDS, liver diseases, oncology and inflammation,
serious respiratory and cardiovascular conditions, headquartered in
Foster City, California. As a Research Scientist, you will join the
Drug Metabolism & Pharmacokinetics (DMPK) group in research,
working closely with biology, protein biochemistry, toxicology,
clinical pharmacology, pharmaceutical sciences, and regulatory to
optimize leads, to select drug candidates for clinical evaluation,
and contribute to IND/ IMPD and NDA/ BLA filings.The primary
responsibilities of this position will be to provide ADME/PK
assessment, modeling and simulation, and project representation to
support discovery and development teams.Job Responsibilities:
- Serve as DMPK subject matter expert on dynamic cross-functional
teams, conduct PK and PBPK analysis, and human efficacious dose
prediction, provide in vitro and in vivo ADME/PK and drug-drug
interaction (DDI) data, interpretation and presentations to
teams.
- Work closely with project teams, line management, internal and
external resources to assure high quality and timely delivery of
drug candidate, documentations for regulatory submissions and
regulatory response.
- Problem-solving ability applying PK, metabolizing enzyme, and
transporter knowledge to mitigate project issues
- Communicate and educate others on areas of ADME science as a
technical expert.
- Makes major contributions to scientific literature and
conferences through publication and presentation of research
results.Knowledge, Experience and Skills:
- Highly motivated individual with a Ph.D. in pharmaceutical
sciences related fields.
- Prior experience and sound knowledge in PK, PK/PD principles,
drug metabolism, and transporter are preferred.
- The candidate will possess strong work ethics, ability to work
independently in a focused, goal-oriented manner. The ability to
interact and collaborate with scientists from various disciplines
and functional areas is vital to this role.
- The candidate will be able to seek evidence of productivity and
independence through authorship of research in peer-reviewed
publications.
- Excellent interpersonal, written and oral communication skills
are prerequisites to perform in a highly-matrixed team
environment.For jobs in the United States:As an equal opportunity
employer, Gilead Sciences Inc. is committed to a diverse workforce.
Employment decisions regarding recruitment and selection will be
made without discrimination based on race, color, religion,
national origin, gender, age, sexual orientation, physical or
mental disability, genetic information or characteristic, gender
identity and expression, veteran status, or other non-job related
characteristics or other prohibited grounds specified in applicable
federal, state and local laws. In order to ensure reasonable
accommodation for individuals protected by Section 503 of the
Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment
Act of 1974, and Title I of the Americans with Disabilities Act of
1990, applicants who require accommodation in the job application
process may contact for assistance.Following extensive monitoring,
research, consideration of business implications and advice from
internal and external experts, Gilead has made the decision to
require all U.S., Canada, Australia, Singapore, and Hong Kong
employees and contractors to receive the COVID-19 vaccines as a
condition of employment. "Full vaccination" is defined as two weeks
after both doses of a two-dose vaccine or two weeks since a
single-dose vaccine has been administered. Anyone unable to be
vaccinated, either because of a sincerely held religious belief or
a medical condition or disability that prevents them from being
vaccinated, can request a reasonable accommodation. For more
information about equal employment opportunity protections, please
view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH
PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT
PAY TRANSPARENCY NONDISCRIMINATION PROVISION Our environment
respects individual differences and recognizes each employee as an
integral member of our company. Our workforce reflects these values
and celebrates the individuals who make up our growing team.Gilead
provides a work environment free of harassment and prohibited
conduct. We promote and support individual differences and
diversity of thoughts and opinion.For Current Gilead Employees and
Contractors:Please log onto your Internal Career Site to apply for
this job.
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Keywords: Gilead Sciences, Inc., San Mateo , Research Scientist, Drug Metabolism and Pharmacokinetics, Other , San Mateo, California
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