Scientist II, Bioanalytical Sciences

Company: Horizon Therapeutics
Location: San Mateo
Posted on: March 20, 2023

Job Description:

Job Description:

At Horizon Therapeutics, we define success by the number of lives touched, lives changed, and lives saved. Our global biotechnology company is made up of agile, out-of-the-box thinkers with a focus on delivering breakthrough medicines to those living with rare, autoimmune, and severe inflammatory diseases. This is the heart of our global mission. Start a career that enables you to live up to your potential and help others live up to theirs. Join us. The exceptional support we provide patients and communities equally extends to our employees. We offer industry-leading and award-winning benefits, compensation and rewards programs that positively impact all areas of our employees' personal and professional lives. Position Summary: Horizon is seeking a highly motivated Manager to support bioanalytical operations for Horizon's nonclinical and clinical programs. ResponsibilitiesSupports the development, qualification, and validation/transfer of PK, ADA, and NAb assays to external CROs and acts as a point of contact with the CROs for sample testingProvides guidance on the design, execution, and interpretation of bioanalytical assays as well as bioanalytical strategies for the organization for both large and small molecule investigative therapeutics. Scientific expert who contributes to responses to questions from regulatory agency on bioassays and immunogenicity. This may be achieved as an individual contributor or by collaborating with different disciplines and across cross functional teamsInvolved in planning experimental design and execution of all aspects of preclinical and clinical bioanalysis, including de novo assay development, optimization, and troubleshootingContributes to multidisciplinary, bioanalytical, regulatory, and clinical team meetingsMaintains accurate and complete safety records consistent with company policy and legal requirements. Recognizes potential safety problems and takes action to rectify themQualifications and Skills RequiredBS or MS in biology, chemistry, biochemistry, biotechnology, or related field.> 5 years in the biopharmaceutical industry, with 3+ years managing CROs.In depth experience in outsourcing the development, validation and execution of ligand binding assays (e.g. ELISA, ECL/MSD) and LC-MS/MS PK assays.Knowledge of assay development and validation, as well as an understanding of GXP requirements and ICH guidelines to support the regulatory approval process.Strong organizational skills and project management experience.Ability to work independently and build open and collaborative relationships.Proficient in Microsoft Office.Professional, proactive demeanor.Strong interpersonal skills.Excellent written and verbal communication skills.Our Values Transparency: We value collaboration. Trusting teach other and tackling tough challenges can make a powerful difference.Accountability: We do what's right for our patient communities through quality decisions and owning our successes and failures.Growth: We fiercely innovate and evolve to better ourselves, our communities and our patients.These three values come to life through our five Leadership Expectations that apply to all Horizon employeesEnterprise Mindset: Look beyond one's team, brand or function to see the broader company and external perspectiveExhibit Intellectual Curiosity: Seek to understand what you do not know; ask the right questions of the right people and sourcesEnsure Accountability and Courage: Step up to address difficult issues and hold self and others accountable to commitmentsEmbrace Diverse Perspectives: Welcome others with a respectful attitude; integrate diverse perspectives into ways of workingDevelop Talent: Provide feedback, coaching and mentorship to help others be more effective in their roleOur ValuesTransparency: We value collaboration. Trusting teach other and tackling tough challenges can make a powerful difference.Accountability: We do what's right for our patient communities through quality decisions and owning our successes and failures.Growth: We fiercely innovate and evolve to better ourselves, our communities and our patients.These three values come to life through our five Leadership Expectations that apply to all Horizon employeesEnterprise Mindset: Look beyond one's team, brand or function to see the broader company and external perspectiveExhibit Intellectual Curiosity: Seek to understand what you do not know; ask the right questions of the right people and sourcesEnsure Accountability and Courage: Step up to address difficult issues and hold self and others accountable to commitmentsEmbrace Diverse Perspectives: Welcome others with a respectful attitude; integrate diverse perspectives into ways of workingDevelop Talent: Provide feedback, coaching and mentorship to help others be more effective in their roleCompensation and Benefits Summary:The salary range for this role is $112,500.00-$137,500.00 annually. The base salary offered may vary based on the final candidate's qualifications. The level of this role may also change based on the final candidate's qualifications.In addition to the salary, this position is eligible for the benefits listed here and for the following plans:Salary Plan, Annual Merit Plan, Annual Equity Grant, New Hire Equity Grant, Corporate BonusAt Horizon, we know that disease does not discriminate. We embrace the bold ideas of one another, foster a sense of belonging, and value inclusion. We attract and develop diverse talent because we believe that when people from different backgrounds and life experiences come together, we make lives better. Horizon intends that all qualified applications are given equal opportunity, and that selection decisions be based on job-related factors. We do not discriminate based on race, color, religion, gender, sexual orientation, national origin, age, disability, veteran status, or any other characteristics protected by law.

Keywords: Horizon Therapeutics, San Mateo , Scientist II, Bioanalytical Sciences, Other , San Mateo, California